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7.7Summary

  • Cancer is the leading cause of death among Japanese population.
  • Cancer derives from canceration of a single cell.
  • Cells exchange information by utilizing a mechanism called signal transduction.
  • Cells proliferate in accordance with the progress of the cell cycle, which is abnormal in cancer cells.
  • Canceration occurs through mechanisms such as chemical carcinogenesis, radiation carcinogenesis, and viral carcinogenesis.
  • Abnormalities in oncogenes and tumor suppressor genes need to accumulate gradually for carcinogenesis.
  • Cancer cells form tumors along with cells in the blood vessels, lymph channels, and immune system.
  • If cancer is left untreated, cancer cells increase their malignancy and metastasize to other organs.
  • Immunotherapy on the basis of immunological facts is in its experimental phase.

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